‘Sure, that is about appropriate. I search for a Bodily idea of biological devices inside of a bottom-up way. I feel you can distinguish 3 strains of research in my group at the moment. The very first problems chromosome framework: how do you have a metre-very long DNA polymer folded and organised in this type of microscopic cell? We have now made visualisation procedures that enable us to check how, as an example, SMC proteins loop DNA (movie on Youtube) so that you can Develop up chromosomes.

Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transportation of macromolecules

Multicolor imaging of your bacterial nucleoid and mobile division proteins with blue, orange, and around-infrared fluorescent proteins

A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola

2012, discovery that nucleoid occlusion underlies the precision of bacterial mobile division; and first ever research of your dynamics DNA supercoils and the discovery of supercoil hopping

The coiled-coil on the human Rad50 DNA restore protein incorporates distinct segments of elevated adaptability

Given that 2000 he moved to single-molecule biophysics and nanobiology, with investigate from DNA supercoiling scientific tests of nucleosomes and DNA mend proteins to DNA translocation by means of nanopores. Not too long ago his study has focused on finding out cell division with bacteria on chip, when his supreme curiosity is during the course of recognizing artificial cells.

Dynamic ParB–DNA interactions initiate and retain a partition condensate for bacterial chromosome segregation

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Dekker began his research on one carbon nanotubes in 1993 when he create a brand new line of research to review electrical transport as a result of solitary organic molecules concerning nanoelectrodes. In 1996 a breakthrough was recognized with carbon nanotubes. This was accomplished inside of a collaboration Together with the group of Nobel laureate Richard Smalley. STM and nanolithography approaches had been utilized to exhibit that these nanotubes are quantum wires at the single-molecule stage, with exceptional Actual physical Homes.

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Afterwards we spoke once more briefly mainly because Dekker ceesdekker.net felt that our dialogue of his religion rapidly grew to become purely philosophical, While What's more, it concretely helps him in his function.

Visualization of unstained DNA nanostructures with State-of-the-art in-aim transmission electron microscopy methods

The biophysicist from Delft – who has become The most cited researchers within the Netherlands For many years – requires his obligation to add on the clarification and popularisation of his function at the border of physics and biology exceptionally severely and often appears in the media; Otherwise to speak about his function, then about the connection involving science and his Christian faith.